About Us

Ascletis is an innovative R&D driven biotech listed on the Hong Kong Stock Exchange (1672.HK). Ascletis is committed to developing and commercializing innovative drugs in the areas of NASH, cancer lipid metabolism and oral checkpoint inhibitors, and viral diseases to address unmet medical needs both in China and globally. Led by a management team with deep expertise and a proven track record, Ascletis has developed into a fully integrated platform covering the entire value chain from discovery and development to manufacturing and commercialization. For more information, please view:  Ascletis Corp Presentation.pdf

Ascletis has three marketed products and a robust R&D pipeline of drug candidates:(1) NASH: Gannex, a wholly-owned company of Ascletis, is dedicated to the R&D and commercialization of new drugs in the field of NASH. Gannex has three clinical stage drug candidates against three different targets – FASN, THRβ and FXR, and three fixed-dose combinations. (2) Cancer lipid metabolism and oral checkpoint inhibitors: a pipeline of oral inhibitors targeting FASN, which plays a key role in cancer lipid metabolism, and a pipeline of oral PD-L1 small molecule next generation checkpoint inhibitors. (3) Viral diseases: (i) Hepatitis B: focus on breakthrough therapies for CHB functional cure with a subcutaneously-injected PD-L1 antibody – ASC22 and Pegasys® as cornerstone drugs. (ii) Hepatitis C: successfully launched an all-oral regimen of combining ASCLEVIR® and GANOVO® (RDV/DNV regimen). (iii) HIV/AIDS: ASC22, an immune therapy to restore HIV-specific immune responses and eventually lead to a functional cure of HIV-infected patients. 

We have built a commercialization team covering five major functions, including medical affairs, sales, marketing strategy, market access, and channel/distribution(GSP). The majority of our commercialization team members have extensive experience working in leading multi-national pharmaceutical companies like Roche, BMS, GSK, Merck and Novartis in China.

Our manufacturing facility located in Shaoxing, Zhejiang province with a total gross floor area of 17,000 square meters. This facility consists of API and formulation production lines, with a designed annual production capacity of 130 million tablets. We have obtained the drug production license for our manufacturing facility and passed GMP inspections by NMPA.


We believe that our integrated platform led by our experienced senior management team will expand our business and deliver sustainable growth in the future. Our platform has enabled us to become a partner-of-choice in China for global leading pharmaceutical companies, as demonstrated by the R&D and commercial collaborations with global pharmaceutical companies such as Roche.